As in-country public health logistics systems become more integrated and sophisticated, many countries are looking to automate their logistics management information systems (LMIS) in order to improve the quantity, quality, and timeliness of logistics data throughout the country. These guidelines were written for managers in the Ministry of Health, program managers, donors, and management information system (MIS) program officers as a reference when considering starting an LMIS automation project, planning for one, and executing that plan. Organized around the phases of a software development project, these guidelines provide practical information and resources to ensure proper program management of a complex technology planning process.